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Histone deacetylase 2–mediated deacetylation of the glucocorticoid receptor enables NF-κB suppression

Glucocorticoids are the most effective antiinflammatory agents for the treatment of chronic inflammatory diseases even though some diseases, such as chronic obstructive pulmonary disease (COPD), are relatively glucocorticoid insensitive. However, the molecular mechanism of this glucocorticoid insens...

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Dades bibliogràfiques
Autors principals: Ito, Kazuhiro, Yamamura, Satoshi, Essilfie-Quaye, Sarah, Cosio, Borja, Ito, Misako, Barnes, Peter J., Adcock, Ian M.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118081/
https://ncbi.nlm.nih.gov/pubmed/16380507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050466
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