Systematic optimization model and algorithm for binding sequence selection in computational enzyme design

por Huang, Xiaoqiang, Han, Kehang, Zhu, Yushan
Publicado em 2013

A Promising Method for Repairing Low-Level Biliary Strictures After Cholecystectomy

por Cheng, Zhilei, Huang, Xiaoqiang, Dong, Jiahong
Publicado no Int Surg (2015)

Copper-catalyzed direct transformation of simple alkynes to alkenyl nitriles via aerobic oxidative N-incorporation

por Huang, Xiaoqiang, Li, Xinyao, Jiao, Ning
Publicado no Chem Sci (2015)

The protective role of microRNA-140-5p in synovial injury of rats with knee osteoarthritis via inactivating the TLR4/Myd88/NF-κB signaling pathway

por Huang, Xiaoqiang, Qiao, Feng, Xue, Peng
Publicado no Cell Cycle (2019)

EvoEF2: accurate and fast energy function for computational protein design

por Huang, Xiaoqiang, Pearce, Robin, Zhang, Yang
Publicado no Bioinformatics (2020)

FASPR: an open-source tool for fast and accurate protein side-chain packing

por Huang, Xiaoqiang, Pearce, Robin, Zhang, Yang
Publicado no Bioinformatics (2020)

De novo design of protein peptides to block association of the SARS-CoV-2 spike protein with human ACE2

por Huang, Xiaoqiang, Pearce, Robin, Zhang, Yang
Publicado no Aging (Albany NY) (2020)

Toward the Accuracy and Speed of Protein Side-Chain Packing: A Systematic Study on Rotamer Libraries

por Huang, Xiaoqiang, Pearce, Robin, Zhang, Yang
Publicado no J Chem Inf Model (2019)

Anticancer effect of xanthohumol induces growth inhibition and apoptosis of human liver cancer through NF-κB/p53-apoptosis signaling pathway

por ZHAO, XIANGQIAN, JIANG, KAI, LIANG, BIN, HUANG, XIAOQIANG
Publicado no Oncol Rep (2016)

Use of an Improved Matching Algorithm to Select Scaffolds for Enzyme Design Based on a Complex Active Site Model

por Huang, Xiaoqiang, Xue, Jing, Lin, Min, Zhu, Yushan
Publicado no PLoS One (2016)

EvoDesign: Designing protein-protein binding interactions using evolutionary interface profiles in conjunction with an optimized physical energy function

por Pearce, Robin, Huang, Xiaoqiang, Setiawan, Dani, Zhang, Yang
Publicado no J Mol Biol (2019)

SSIPe: accurately estimating protein–protein binding affinity change upon mutations using evolutionary profiles in combination with an optimized physical energy function

por Huang, Xiaoqiang, Zheng, Wei, Pearce, Robin, Zhang, Yang
Publicado no Bioinformatics (2020)

Identification of 13 Guanidinobenzoyl- or Aminidinobenzoyl-Containing Drugs to Potentially Inhibit TMPRSS2 for COVID-19 Treatment

por Huang, Xiaoqiang, Pearce, Robin, Omenn, Gilbert S., Zhang, Yang
Publicado no Int J Mol Sci (2021)

Rational Design of SARS-CoV-2 Spike Glycoproteins To Increase Immunogenicity By T Cell Epitope Engineering

por Ong, Edison, Huang, Xiaoqiang, Pearce, Robin, Zhang, Yang, He, Yongqun
Publicado no bioRxiv (2020)

Identifying zoonotic origin of SARS-CoV-2 by modeling the binding affinity between Spike receptor-binding domain and host ACE2

por Huang, Xiaoqiang, Zhang, Chengxin, Pearce, Robin, Omenn, Gilbert S., Zhang, Yang
Publicado no bioRxiv (2020)

Identifying the Zoonotic Origin of SARS-CoV-2 by Modeling the Binding Affinity Between the Spike Receptor-Binding Domain and Host ACE2

por Huang, Xiaoqiang, Zhang, Chengxin, Pearce, Robin, Omenn, Gilbert S., Zhang, Yang
Publicado no J Proteome Res (2020)

Computational design of SARS-CoV-2 spike glycoproteins to increase immunogenicity by T cell epitope engineering

por Ong, Edison, Huang, Xiaoqiang, Pearce, Robin, Zhang, Yang, He, Yongqun
Publicado no Comput Struct Biotechnol J (2020)

Catalytic asymmetric synthesis of a nitrogen heterocycle through stereocontrolled direct photoreaction from electronically excited state

por Huang, Xiaoqiang, Li, Xinyao, Xie, Xiulan, Harms, Klaus, Riedel, Radostan, Meggers, Eric
Publicado no Nat Commun (2017)

The application of vascularized stomach flap to repair postoperative biliary stricture

por Zeng, Jianping, Wang, Jing, Dong, Jiahong, Huang, Xiaoqiang, Xia, Hongtian, Xiang, Xin
Publicado no Medicine (Baltimore) (2018)

Combining the catalytic enantioselective reaction of visible-light-generated radicals with a by-product utilization system

por Huang, Xiaoqiang, Luo, Shipeng, Burghaus, Olaf, Webster, Richard D., Harms, Klaus, Meggers, Eric
Publicado no Chem Sci (2017)