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Rational Design of SARS-CoV-2 Spike Glycoproteins To Increase Immunogenicity By T Cell Epitope Engineering

The current COVID-19 pandemic caused by SARS-CoV-2 has resulted in millions of confirmed cases and thousands of deaths globally. Extensive efforts and progress have been made to develop effective and safe vaccines against COVID-19. A primary target of these vaccines is the SARS-CoV-2 spike (S) prote...

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Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Ong, Edison, Huang, Xiaoqiang, Pearce, Robin, Zhang, Yang, He, Yongqun
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430581/
https://ncbi.nlm.nih.gov/pubmed/32817949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.08.14.251496
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