CD38 in Adenosinergic Pathways and Metabolic Re-programming in Human Multiple Myeloma Cells: In-tandem Insights From Basic Science to Therapy

Por Horenstein, Alberto L., Bracci, Cristiano, Morandi, Fabio, Malavasi, Fabio
Publicado no Front Immunol (2019)

Microvesicles expressing adenosinergic ectoenzymes and their potential role in modulating bone marrow infiltration by neuroblastoma cells

Por Morandi, Fabio, Marimpietri, Danilo, Horenstein, Alberto L., Corrias, Maria Valeria, Malavasi, Fabio
Publicado no Oncoimmunology (2019)

Roles and Modalities of Ectonucleotidases in Remodeling the Multiple Myeloma Niche

Por Chillemi, Antonella, Quarona, Valeria, Antonioli, Luca, Ferrari, Davide, Horenstein, Alberto L., Malavasi, Fabio
Publicado no Front Immunol (2017)

CD38: A Target for Immunotherapeutic Approaches in Multiple Myeloma

Por Morandi, Fabio, Horenstein, Alberto L., Costa, Federica, Giuliani, Nicola, Pistoia, Vito, Malavasi, Fabio
Publicado no Front Immunol (2018)

Role of CD31/Platelet Endothelial Cell Adhesion Molecule-1 Expression in in Vitro and in Vivo Growth and Differentiation of Human Breast Cancer Cells

Por Righi, Luisella, Deaglio, Silvia, Pecchioni, Carla, Gregorini, Armando, Horenstein, Alberto L., Bussolati, Gianni, Sapino, Anna, Malavasi, Fabio
Publicado em 2003

Anti-CD38 Antibody Therapy: Windows of Opportunity Yielded by the Functional Characteristics of the Target Molecule

Por Chillemi, Antonella, Zaccarello, Gianluca, Quarona, Valeria, Ferracin, Manuela, Ghimenti, Chiara, Massaia, Massimo, Horenstein, Alberto L, Malavasi, Fabio
Publicado em 2013

A CD38/CD203a/CD73 ectoenzymatic pathway independent of CD39 drives a novel adenosinergic loop in human T lymphocytes

Por Horenstein, Alberto L, Chillemi, Antonella, Zaccarello, Gianluca, Bruzzone, Santina, Quarona, Valeria, Zito, Andrea, Serra, Sara, Malavasi, Fabio
Publicado em 2013

Adenosine Generated in the Bone Marrow Niche Through a CD38-Mediated Pathway Correlates With Progression of Human Myeloma

Por Horenstein, Alberto L, Quarona, Valeria, Toscani, Denise, Costa, Federica, Chillemi, Antonella, Pistoia, Vito, Giuliani, Nicola, Malavasi, Fabio
Publicado no Mol Med (2016)

CD38 and CD157 Ectoenzymes Mark Cell Subsets in the Human Corneal Limbus

Por Horenstein, Alberto L, Sizzano, Federico, Lusso, Riccardo, Besso, Federico Genzano, Ferrero, Enza, Deaglio, Silvia, Corno, Franco, Malavasi, Fabio
Publicado em 2009

CD38 modulates respiratory syncytial virus‐driven proinflammatory processes in human monocyte‐derived dendritic cells

Por Schiavoni, Ilaria, Scagnolari, Carolina, Horenstein, Alberto L., Leone, Pasqualina, Pierangeli, Alessandra, Malavasi, Fabio, Ausiello, Clara M., Fedele, Giorgio
Publicado no Immunology (2017)

CD38 Ligation in Peripheral Blood Mononuclear Cells of Myeloma Patients Induces Release of Protumorigenic IL-6 and Impaired Secretion of IFNγ Cytokines and Proliferation

Por Fedele, Giorgio, Di Girolamo, Marco, Recine, Umberto, Palazzo, Raffaella, Urbani, Francesca, Horenstein, Alberto L., Malavasi, Fabio, Ausiello, Clara Maria
Publicado em 2013

A Murine, Bispecific Monoclonal Antibody Simultaneously Recognizing β-Glucan and MP65 Determinants in Candida Species

Por Zito, Andrea, Bromuro, Carla, Mandili, Giorgia, Chiani, Paola, Horenstein, Alberto L., Malavasi, Fabio, Cauda, Roberto, Cassone, Antonio, Torosantucci, Antonella
Publicado no PLoS One (2016)

Cytokine-Induced Killer Cells Express CD39, CD38, CD203a, CD73 Ectoenzymes and P1 Adenosinergic Receptors

Por Horenstein, Alberto L., Chillemi, Antonella, Zini, Roberta, Quarona, Valeria, Bianchi, Nicoletta, Manfredini, Rossella, Gambari, Roberto, Malavasi, Fabio, Ferrari, Davide
Publicado no Front Pharmacol (2018)

The CD157-Integrin Partnership Controls Transendothelial Migration and Adhesion of Human Monocytes

Por Lo Buono, Nicola, Parrotta, Rossella, Morone, Simona, Bovino, Paola, Nacci, Giulia, Ortolan, Erika, Horenstein, Alberto L., Inzhutova, Alona, Ferrero, Enza, Funaro, Ada
Publicado em 2011

Stable coordination of the inhibitory Ca(2+) ion at MIDAS in integrin CD11b/CD18 by an antibody-derived ligand aspartate: Implications for integrin regulation and structure-based d...

Por Mahalingam, Bhuvaneshwari, Ajroud, Kaouther, Alonso, Jose Luis, Anand, Saurabh, Adair, Brian, Horenstein, Alberto L, Malavasi, Fabio, Xiong, Jian-Ping, Arnaout, M. Amin
Publicado em 2011

A non-canonical adenosinergic pathway led by CD38 in human melanoma cells induces suppression of T cell proliferation

Por Morandi, Fabio, Morandi, Barbara, Horenstein, Alberto L., Chillemi, Antonella, Quarona, Valeria, Zaccarello, Gianluca, Carrega, Paolo, Ferlazzo, Guido, Mingari, Maria Cristina, Moretta, Lorenzo, Pistoia, Vito, Malavasi, Fabio
Publicado no Oncotarget (2015)

CD73-generated extracellular adenosine in chronic lymphocytic leukemia creates local conditions counteracting drug-induced cell death

Por Serra, Sara, Horenstein, Alberto L., Vaisitti, Tiziana, Brusa, Davide, Rossi, Davide, Laurenti, Luca, D'Arena, Giovanni, Coscia, Marta, Tripodo, Claudio, Inghirami, Giorgio, Robson, Simon C., Gaidano, Gianluca, Malavasi, Fabio, Deaglio, Silvia
Publicado em 2011

NAD(+)-Metabolizing Ectoenzymes in Remodeling Tumor–Host Interactions: The Human Myeloma Model

Por Horenstein, Alberto L., Chillemi, Antonella, Quarona, Valeria, Zito, Andrea, Roato, Ilaria, Morandi, Fabio, Marimpietri, Danilo, Bolzoni, Marina, Toscani, Denise, Oldham, Robert J., Cuccioloni, Massimiliano, Sasser, A. Kate, Pistoia, Vito, Giuliani, Nicola, Malavasi, Fabio
Publicado no Cells (2015)

CD38 and CD157 as Receptors of the Immune System: A Bridge Between Innate and Adaptive Immunity

Por Malavasi, Fabio, Deaglio, Silvia, Ferrero, Enza, Funaro, Ada, Sancho, Jaime, Ausiello, Clara M, Ortolan, Erika, Vaisitti, Tiziana, Zubiaur, Mercedes, Fedele, Giorgio, Aydin, Semra, Tibaldi, Elena V, Durelli, Ilaria, Lusso, Riccardo, Cozno, Franco, Horenstein, Alberto L
Publicado em 2006

Expression of CD38 in myeloma bone niche: A rational basis for the use of anti-CD38 immunotherapy to inhibit osteoclast formation

Por Costa, Federica, Toscani, Denise, Chillemi, Antonella, Quarona, Valeria, Bolzoni, Marina, Marchica, Valentina, Vescovini, Rosanna, Mancini, Cristina, Martella, Eugenia, Campanini, Nicoletta, Schifano, Chiara, Bonomini, Sabrina, Accardi, Fabrizio, Horenstein, Alberto L., Aversa, Franco, Malavasi, Fabio, Giuliani, Nicola
Publicado no Oncotarget (2017)