Roles and Modalities of Ectonucleotidases in Remodeling the Multiple Myeloma Niche

Ectoenzymes are cell surface molecules, which represent functional bridges between the environment and the cytoplasm. One set of ectoenzymes—CD39, CD38, CD203a, and CD73—leads to the generation of adenosine (ADO) by metabolizing ATP and NAD(+). While ADO is known to control inflammation and suppress...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Chillemi, Antonella, Quarona, Valeria, Antonioli, Luca, Ferrari, Davide, Horenstein, Alberto L., Malavasi, Fabio
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357780/
https://ncbi.nlm.nih.gov/pubmed/28373875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00305
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