A non-canonical adenosinergic pathway led by CD38 in human melanoma cells induces suppression of T cell proliferation

Nucleotide-metabolizing ectoenzymes are endowed with an extracellular catalytic domain, which is involved in regulating the extracellular nucleotide/nucleoside balance. The tumor microenvironment contains high levels of adenosine (ADO) generated by this enzymatic network, thus promoting tumor growth...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Morandi, Fabio, Morandi, Barbara, Horenstein, Alberto L., Chillemi, Antonella, Quarona, Valeria, Zaccarello, Gianluca, Carrega, Paolo, Ferlazzo, Guido, Mingari, Maria Cristina, Moretta, Lorenzo, Pistoia, Vito, Malavasi, Fabio
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694853/
https://ncbi.nlm.nih.gov/pubmed/26329660
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