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A CD38/CD203a/CD73 ectoenzymatic pathway independent of CD39 drives a novel adenosinergic loop in human T lymphocytes

The tumor microenvironment is characterized by of high levels of extracellular nucleotides that are metabolized through the dynamic and sequential action of cell surface enzymes (ectoenzymes). These ectoenzymes operate according to their spatial arrangement, as part of (1) continuous (molecules on t...

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Detalhes bibliográficos
Main Authors: Horenstein, Alberto L, Chillemi, Antonella, Zaccarello, Gianluca, Bruzzone, Santina, Quarona, Valeria, Zito, Andrea, Serra, Sara, Malavasi, Fabio
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3850273/
https://ncbi.nlm.nih.gov/pubmed/24319640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.26246
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