The effect of using a robust optimality criterion in model based adaptive optimization

Por Strömberg, Eric A., Hooker, Andrew C.
Publicado no J Pharmacokinet Pharmacodyn (2017)

Preconditioning of Nonlinear Mixed Effects Models for Stabilisation of Variance-Covariance Matrix Computations

Por Aoki, Yasunori, Nordgren, Rikard, Hooker, Andrew C.
Publicado no AAPS J (2016)

Accelerating Monte Carlo power studies through parametric power estimation

Por Ueckert, Sebastian, Karlsson, Mats O., Hooker, Andrew C.
Publicado no J Pharmacokinet Pharmacodyn (2016)

The effect of Fisher information matrix approximation methods in population optimal design calculations

Por Strömberg, Eric A., Nyberg, Joakim, Hooker, Andrew C.
Publicado no J Pharmacokinet Pharmacodyn (2016)

Model selection and averaging of nonlinear mixed-effect models for robust phase III dose selection

Por Aoki, Yasunori, Röshammar, Daniel, Hamrén, Bengt, Hooker, Andrew C.
Publicado no J Pharmacokinet Pharmacodyn (2017)

Estimation of drug receptor occupancy when non-displaceable binding differs between brain regions – extending the simplified reference tissue model

Por Kågedal, Matts, Varnäs, Katarina, Hooker, Andrew C, Karlsson, Mats O
Publicado no Br J Clin Pharmacol (2015)

Prediction-Corrected Visual Predictive Checks for Diagnosing Nonlinear Mixed-Effects Models

Por Bergstrand, Martin, Hooker, Andrew C., Wallin, Johan E., Karlsson, Mats O.
Publicado em 2011

Optimal Design in Population Kinetic Experiments by Set-Valued Methods

Por Gennemark, Peter, Danis, Alexander, Nyberg, Joakim, Hooker, Andrew C., Tucker, Warwick
Publicado em 2011

Modeling Subpopulations with the $MIXTURE Subroutine in NONMEM: Finding the Individual Probability of Belonging to a Subpopulation for the Use in Model Analysis and Improved Decisi...

Por Carlsson, Kristin C., Savi, Radojka M., Hooker, Andrew C., Karlsson, Mats O.
Publicado em 2009

A Fast Method for Testing Covariates in Population PK/PD Models

Por Khandelwal, Akash, Harling, Kajsa, Jonsson, E. Niclas, Hooker, Andrew C., Karlsson, Mats O.
Publicado em 2011

Improved Utilization of ADAS-Cog Assessment Data Through Item Response Theory Based Pharmacometric Modeling

Por Ueckert, Sebastian, Plan, Elodie L., Ito, Kaori, Karlsson, Mats O., Corrigan, Brian, Hooker, Andrew C.
Publicado em 2014

Multinomial Logistic Functions in Markov Chain Models of Sleep Architecture: Internal and External Validation and Covariate Analysis

Por Bizzotto, Roberto, Zamuner, Stefano, Mezzalana, Enrica, De Nicolao, Giuseppe, Gomeni, Roberto, Hooker, Andrew C., Karlsson, Mats O.
Publicado em 2011

Methods and software tools for design evaluation in population pharmacokinetics–pharmacodynamics studies

Por Nyberg, Joakim, Bazzoli, Caroline, Ogungbenro, Kay, Aliev, Alexander, Leonov, Sergei, Duffull, Stephen, Hooker, Andrew C, Mentré, France
Publicado no Br J Clin Pharmacol (2015)

Model Description Language (MDL): A Standard for Modeling and Simulation

Por Smith, Mike K., Moodie, Stuart L., Bizzotto, Roberto, Blaudez, Eric, Borella, Elisa, Carrara, Letizia, Chan, Phylinda, Chenel, Marylore, Comets, Emmanuelle, Gieschke, Ronald, Harling, Kajsa, Harnisch, Lutz, Hartung, Niklas, Hooker, Andrew C., Karlsson, Mats O., Kaye, Richard, Kloft, Charlotte, Kokash, Natallia, Lavielle, Marc, Lestini, Giulia, Magni, Paolo, Mari, Andrea, Mentré, France, Muselle, Chris, Nordgren, Rikard, Nyberg, Henrik B., Parra‐Guillén, Zinnia P., Pasotti, Lorenzo, Rode‐Kristensen, Niels, Sardu, Maria L., Smith, Gareth R., Swat, Maciej J., Terranova, Nadia, Yngman, Gunnar, Yvon, Florent, Holford, Nick
Publicado no CPT Pharmacometrics Syst Pharmacol (2017)