An Efficient Algorithm to Perform Local Concerted Movements of a Chain Molecule

par Zamuner, Stefano, Rodriguez, Alex, Seno, Flavio, Trovato, Antonio
Publié dans PLoS One (2015)

A common root for coevolution and substitution rate variability in protein sequence evolution

par Rizzato, Francesca, Zamuner, Stefano, Pagnani, Andrea, Laio, Alessandro
Publié dans Sci Rep (2019)

The Orexin Antagonist SB-649868 Promotes and Maintains Sleep in Men with Primary Insomnia

par Bettica, Paolo, Squassante, Lisa, Zamuner, Stefano, Nucci, Gianluca, Danker-Hopfe, Heidi, Ratti, Emiliangelo
Publié 2012

Mechanics of Allostery: Contrasting the Induced Fit and Population Shift Scenarios

par Ravasio, Riccardo, Flatt, Solange Marie, Yan, Le, Zamuner, Stefano, Brito, Carolina, Wyart, Matthieu
Publié dans Biophys J (2019)

Multinomial Logistic Functions in Markov Chain Models of Sleep Architecture: Internal and External Validation and Covariate Analysis

par Bizzotto, Roberto, Zamuner, Stefano, Mezzalana, Enrica, De Nicolao, Giuseppe, Gomeni, Roberto, Hooker, Andrew C., Karlsson, Mats O.
Publié 2011

Thermodynamics and kinetics of protonated merocyanine photoacids in water

par Berton, Cesare, Busiello, Daniel Maria, Zamuner, Stefano, Solari, Euro, Scopelliti, Rosario, Fadaei-Tirani, Farzaneh, Severin, Kay, Pezzato, Cristian
Publié dans Chem Sci (2020)

Effect of single and repeat doses of casopitant on the pharmacokinetics of CYP450 3A4 substrates midazolam and nifedipine

par Zamuner, Stefano, Johnson, Brendan M, Pagliarusco, Sabrina, Fina, Paolo, Peroni, Michela, Fiore, Monica, Adams, Laurel M, Fernandes, Sofia A
Publié 2010

In vivo affinity and target engagement in skin and blood in a first‐time‐in‐human study of an anti‐oncostatin M monoclonal antibody

par Reid, Juliet, Zamuner, Stefano, Edwards, Ken, Rumley, Sally‐Anne, Nevin, Katherine, Feeney, Maria, Zecchin, Chiara, Fernando, Disala, Wisniacki, Nicolas
Publié dans Br J Clin Pharmacol (2018)

Safety, tolerability, pharmacokinetics and pharmacodynamics of an anti- oncostatin M monoclonal antibody in rheumatoid arthritis: results from phase II randomized, placebo-controll...

par Choy, Ernest H, Bendit, Marina, McAleer, Dana, Liu, Feng, Feeney, Maria, Brett, Sara, Zamuner, Stefano, Campanile, Andrea, Toso, John
Publié 2013

Central nervous system effects of the interaction between risperidone (single dose) and the 5-HT(6) antagonist SB742457 (repeated doses) in healthy men

par Liem-Moolenaar, Marieke, Rad, Mandana, Zamuner, Stefano, Cohen, Adam F, Lemme, Francesca, Franson, Kari L, van Gerven, Joop M A, Pich, Emilio Merlo
Publié 2011

Computational pipeline to probe NaV1.7 gain-of-function variants in neuropathic painful syndromes

par Toffano, Alberto A., Chiarot, Giacomo, Zamuner, Stefano, Marchi, Margherita, Salvi, Erika, Waxman, Stephen G., Faber, Catharina G., Lauria, Giuseppe, Giacometti, Achille, Simeoni, Marta
Publié dans Sci Rep (2020)

Efficacy of Vestipitant, A Neurokinin-1 Receptor Antagonist, in Primary Insomnia

par Ratti, Emiliangelo, Carpenter, David J., Zamuner, Stefano, Fernandes, Sofia, Squassante, Lisa, Danker-Hopfe, Heidi, Archer, Graeme, Robertson, Jonathan, Alexander, Robert, Trist, David G., Merlo-Pich, Emilio
Publié 2013

CCL20 neutralization by a monoclonal antibody in healthy subjects selectively inhibits recruitment of CCR6(+) cells in an experimental suction blister

par Bouma, Gerben, Zamuner, Stefano, Hicks, Kirsty, Want, Andrew, Oliveira, João, Choudhury, Arpita, Brett, Sara, Robertson, Darren, Felton, Leigh, Norris, Virginia, Fernando, Disala, Herdman, Michael, Tarzi, Ruth
Publié dans Br J Clin Pharmacol (2017)

Self-Organization of parS Centromeres by the ParB CTP Hydrolase

par Soh, Young-Min, Davidson, Iain Finley, Zamuner, Stefano, Basquin, Jérôme, Bock, Florian Patrick, Taschner, Michael, Veening, Jan-Willem, De Los Rios, Paolo, Peters, Jan-Michael, Gruber, Stephan
Publié dans Science (2019)

Mathematical Modelling of Alternative Pathway of Complement System

par Bakshi, Suruchi, Cunningham, Fraser, Nichols, Eva-Maria, Biedzka-Sarek, Marta, Neisen, Jessica, Petit-Frere, Sebastien, Bessant, Christina, Bansal, Loveleena, Peletier, Lambertus A., Zamuner, Stefano, van der Graaf, Piet H.
Publié dans Bull Math Biol (2020)

Target engagement and cellular fate of otelixizumab: a repeat dose escalation study of an anti‐CD3ε mAb in new‐onset type 1 diabetes mellitus patients

par Vlasakakis, Georgios, Napolitano, Antonella, Barnard, Ruth, Brown, Kim, Bullman, Jonathan, Inman, David, Keymeulen, Bart, Lanham, David, Leirens, Quentin, MacDonald, Alexander, Mezzalana, Enrica, Page, Kevin, Patel, Minesh, Savage, Caroline O., Zamuner, Stefano, van Maurik, Andre
Publié dans Br J Clin Pharmacol (2019)

Prediction of repeat-dose occupancy from single-dose data: characterisation of the relationship between plasma pharmacokinetics and brain target occupancy

par Abanades, Sergio, van der Aart, Jasper, Barletta, Julien AR, Marzano, Carmine, Searle, Graham E, Salinas, Cristian A, Ahmad, Javaad J, Reiley, Richard R, Pampols-Maso, Sabina, Zamuner, Stefano, Cunningham, Vincent J, Rabiner, Eugenii A, Laruelle, Marc A, Gunn, Roger N
Publié 2011