Self-Organization of parS Centromeres by the ParB CTP Hydrolase

ParABS systems facilitate chromosome segregation and plasmid partitioning in bacteria and archaea. ParB protein binds centromeric parS DNA sequences and spreads to flanking DNA. We show that ParB is an enzyme that hydrolyzes cytidine triphosphate (CTP) to diphosphate (CDP). parS DNA stimulates coope...

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Publicado no:Science
Main Authors: Soh, Young-Min, Davidson, Iain Finley, Zamuner, Stefano, Basquin, Jérôme, Bock, Florian Patrick, Taschner, Michael, Veening, Jan-Willem, De Los Rios, Paolo, Peters, Jan-Michael, Gruber, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927813/
https://ncbi.nlm.nih.gov/pubmed/31649139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aay3965
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