Self-Organization of parS Centromeres by the ParB CTP Hydrolase

ParABS systems facilitate chromosome segregation and plasmid partitioning in bacteria and archaea. ParB protein binds centromeric parS DNA sequences and spreads to flanking DNA. We show that ParB is an enzyme that hydrolyzes cytidine triphosphate (CTP) to diphosphate (CDP). parS DNA stimulates coope...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Science
Prif Awduron: Soh, Young-Min, Davidson, Iain Finley, Zamuner, Stefano, Basquin, Jérôme, Bock, Florian Patrick, Taschner, Michael, Veening, Jan-Willem, De Los Rios, Paolo, Peters, Jan-Michael, Gruber, Stephan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927813/
https://ncbi.nlm.nih.gov/pubmed/31649139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aay3965
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