Self-Organization of parS Centromeres by the ParB CTP Hydrolase

ParABS systems facilitate chromosome segregation and plasmid partitioning in bacteria and archaea. ParB protein binds centromeric parS DNA sequences and spreads to flanking DNA. We show that ParB is an enzyme that hydrolyzes cytidine triphosphate (CTP) to diphosphate (CDP). parS DNA stimulates coope...

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Bibliographic Details
Published in:Science
Main Authors: Soh, Young-Min, Davidson, Iain Finley, Zamuner, Stefano, Basquin, Jérôme, Bock, Florian Patrick, Taschner, Michael, Veening, Jan-Willem, De Los Rios, Paolo, Peters, Jan-Michael, Gruber, Stephan
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927813/
https://ncbi.nlm.nih.gov/pubmed/31649139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aay3965
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