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Self-Organization of parS Centromeres by the ParB CTP Hydrolase
ParABS systems facilitate chromosome segregation and plasmid partitioning in bacteria and archaea. ParB protein binds centromeric parS DNA sequences and spreads to flanking DNA. We show that ParB is an enzyme that hydrolyzes cytidine triphosphate (CTP) to diphosphate (CDP). parS DNA stimulates coope...
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| Published in: | Science |
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| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6927813/ https://ncbi.nlm.nih.gov/pubmed/31649139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aay3965 |
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