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Mechanics of Allostery: Contrasting the Induced Fit and Population Shift Scenarios
In allosteric proteins, binding a ligand can affect function at a distant location, for example, by changing the binding affinity of a substrate at the active site. The induced fit and population shift models, which differ by the assumed number of stable configurations, explain such cooperative bind...
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| Veröffentlicht in: | Biophys J |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7031744/ https://ncbi.nlm.nih.gov/pubmed/31653447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.10.002 |
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