Učitavanje...
Allostery and population shift in drug discovery
Proteins can exist in a large number of conformations around their native states that can be characterized by an energy landscape. The landscape illustrates individual valleys, which are the conformational substates. From the functional standpoint, there are two key points: first, all functionally r...
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| Izdano u: | Curr Opin Pharmacol |
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| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7316380/ https://ncbi.nlm.nih.gov/pubmed/20884293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2010.09.002 |
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