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Proteasome allostery as a population shift between interchanging conformers
Protein degradation plays a critical role in cellular homeostasis, in regulating the cell cycle, and in the generation of peptides that are used in the immune response. The 20S proteasome core particle (CP), a barrel-like structure consisting of four heptameric protein rings stacked axially on top o...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3528551/ https://ncbi.nlm.nih.gov/pubmed/23150576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213640109 |
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