Norbenzomorphan Framework as a Novel Scaffold for Generating Sigma 2 Receptor/PGRMC1 Subtype Selective Ligands

מאת Sahn, James J., Hodges, Timothy R., Chan, Jessica Z., Martin, Stephen F.
הוצא לאור ב ChemMedChem (2016)

Norbenzomorphan Scaffold: Chemical Tool for Modulating Sigma Receptor-Subtype Selectivity

מאת Sahn, James J., Hodges, Timothy R., Chan, Jessica Z., Martin, Stephen F.
הוצא לאור ב ACS Med Chem Lett (2017)

High-Content Microfluidic Screening Platform Used To Identify σ2R/Tmem97 Binding Ligands that Reduce Age-Dependent Neurodegeneration in C. elegans SC_APP Model

מאת Monda, Sudip, Hegarty, Evan, Sahn, James J., Scott, Luisa L., Gökçe, Sertan Kutal, Martin, Chris, Ghorashian, Navid, Satarasinghe, Praveen Navoda, Iyer, Sangeetha, Sae-Lee, Wisath, Hodges, Timothy R., Pierce, Jonathan T., Martin, Stephen F., Ben-Yakar, Adela
הוצא לאור ב ACS Chem Neurosci (2018)

Small molecule modulators of σ2R/Tmem97 reduce alcohol withdrawal-induced behaviors

מאת Scott, Luisa L., Sahn, James J., Ferragud, Antonio, Yen, Rachel C., Satarasinghe, Praveen N., Wood, Michael D., Hodges, Timothy R., Shi, Ted, Prakash, Brooke A., Friese, Kaitlyn M., Shen, Angela, Sabino, Valentina, Pierce, Jonathan T., Martin, Stephen F.
הוצא לאור ב Neuropsychopharmacology (2018)

Neuroprotective Efficacy of a Sigma 2 Receptor/TMEM97 Modulator (DKR-1677) after Traumatic Brain Injury

מאת Vázquez-Rosa, Edwin, Watson, Michael R., Sahn, James J., Hodges, Timothy R., Schroeder, Rachel E., Cintrón-Pérez, Coral J., Shin, Min-Kyoo, Yin, Terry C., Emery, Josie L., Martin, Stephen F., Liebl, Daniel J., Pieper, Andrew A.
הוצא לאור ב ACS Chem Neurosci (2018)

Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS

מאת Hodges, Timothy R., Abbott, Jason R., Little, Andrew J., Sarkar, Dhruba, Salovich, James M., Howes, Jennifer E., Akan, Denis T., Sai, Jiqing, Arnold, Allison L., Browning, Carrie, Burns, Michael C., Sobolik, Tammy, Sun, Qi, Beesetty, Yugandhar, Coker, Jesse A., Scharn, Dirk, Stadtmueller, Heinz, Rossanese, Olivia W., Phan, Jason, Waterson, Alex G., McConnell, Darryl B., Fesik, Stephen W.
הוצא לאור ב J Med Chem (2018)