Direct binding to antigen-coated beads refines the specificity and cross-reactivity of four monoclonal antibodies that recognize polymorphic epitopes of HLA class I molecules

par Hilton, Hugo G, Parham, Peter
Publié 2013

Missing or altered self: human NK cell receptors that recognize HLA-C

par Hilton, Hugo G., Parham, Peter
Publié dans Immunogenetics (2017)

Co-evolution of MHC class I and variable NK cell receptors in placental mammals

par Guethlein, Lisbeth A., Norman, Paul J., Hilton, Hugo G., Parham, Peter
Publié dans Immunol Rev (2015)

Deciphering the killer‐cell immunoglobulin‐like receptor system at super‐resolution for natural killer and T‐cell biology

par Béziat, Vivien, Hilton, Hugo G., Norman, Paul J., Traherne, James A.
Publié dans Immunology (2016)

Immunogenetics of Human Placentation

par Parham, Peter, Norman, Paul J., Abi-Rached, Laurent, Hilton, Hugo G., Guethlein, Lisbeth A.
Publié 2011

Resurrecting KIR2DP1 a Key Intermediate in the Evolution of Human Inhibitory NK cell Receptors that Recognize HLA-C

par Hilton, Hugo G., Blokhuis, Jeroen H., Guethlein, Lisbeth A., Norman, Paul J., Parham, Peter
Publié dans J Immunol (2017)

The production of KIR-Fc fusion proteins and their use in a multiplex HLA class I binding assay

par Hilton, Hugo G., Moesta, Achim K., Guethlein, Lisbeth A., Blokhuis, Jeroen, Parham, Peter, Norman, Paul J.
Publié dans J Immunol Methods (2015)

A Distinctive Cytoplasmic Tail Contributes to Low Surface Expression and Intracellular Retention of the Patr-AL MHC class I molecule()

par Goyos, Ana, Guethlein, Lisbeth A., Horowitz, Amir, Hilton, Hugo G., Gleimer, Michael, Brodsky, Frances M., Parham, Peter
Publié dans J Immunol (2015)

Polymorphic HLA-C receptors balance the functional characteristics of KIR haplotypes

par Hilton, Hugo G., Guethlein, Lisbeth A., Goyos, Ana, Nemat-Gorgani, Neda, Bushnell, David A., Norman, Paul J., Parham, Peter
Publié dans J Immunol (2015)

KIR2DS5 allotypes that recognize the C2 epitope of HLA‐C are common among Africans and absent from Europeans

par Blokhuis, Jeroen H., Hilton, Hugo G., Guethlein, Lisbeth A., Norman, Paul J., Nemat‐Gorgani, Neda, Nakimuli, Annettee, Chazara, Olympe, Moffett, Ashley, Parham, Peter
Publié dans Immun Inflamm Dis (2017)

Loss and Gain of Natural Killer Cell Receptor Function in an African Hunter-Gatherer Population

par Hilton, Hugo G., Norman, Paul J., Nemat-Gorgani, Neda, Goyos, Ana, Hollenbach, Jill A., Henn, Brenna M., Gignoux, Christopher R., Guethlein, Lisbeth A., Parham, Peter
Publié dans PLoS Genet (2015)

Class I HLA haplotypes form two schools that educate NK cells in different ways

par Horowitz, Amir, Djaoud, Zakia, Nemat-Gorgani, Neda, Blokhuis, Jeroen, Hilton, Hugo G., Béziat, Vivien, Malmberg, Karl-Johan, Norman, Paul J., Guethlein, Lisbeth A., Parham, Peter
Publié dans Sci Immunol (2016)

Mutation at Positively Selected Positions in the Binding site for HLA-C Shows KIR2DL1 is a More Refined but Less Adaptable NK cell Receptor than KIR2DL3()

par Hilton, Hugo G., Vago, Luca, Older Aguilar, Ana, Moesta, Achim K., Graef, Thorsten, Abi Rached, Laurent, Norman, Paul J., Guethlein, Lisbeth A., Fleischhauer, Katharina, Parham, Peter
Publié 2012

Two Orangutan Species Have Evolved Different KIR Alleles and Haplotypes

par Guethlein, Lisbeth A., Norman, Paul J., Heijmans, Corinne M. C., de Groot, Natasja G., Hilton, Hugo G., Babrzadeh, Farbod, Abi-Rached, Laurent, Bontrop, Ronald E., Parham, Peter
Publié dans J Immunol (2017)

Genetic diversity affects the nanoscale membrane organization and signaling of natural killer cell receptors

par Kennedy, Philippa R., Barthen, Charlotte, Williamson, David J., Pitkeathly, W. T. Eric, Hazime, Khodor S., Cumming, Joshua, Stacey, Kevin B., Hilton, Hugo G., Carrington, Mary, Parham, Peter, Davis, Daniel M.
Publié dans Sci Signal (2019)

Co-evolution of Human Leukocyte Antigen (HLA) Class I Ligands with Killer-Cell Immunoglobulin-Like Receptors (KIR) in a Genetically Diverse Population of Sub-Saharan Africans

par Norman, Paul J., Hollenbach, Jill A., Nemat-Gorgani, Neda, Guethlein, Lisbeth A., Hilton, Hugo G., Pando, Marcelo J., Koram, Kwadwo A., Riley, Eleanor M., Abi-Rached, Laurent, Parham, Peter
Publié 2013

Single-cell transcriptomics of the naked mole-rat reveals unexpected features of mammalian immunity

par Hilton, Hugo G., Rubinstein, Nimrod D., Janki, Peter, Ireland, Andrea T., Bernstein, Nicholas, Fong, Nicole L., Wright, Kevin M., Smith, Megan, Finkle, David, Martin-McNulty, Baby, Roy, Margaret, Imai, Denise M., Jojic, Vladimir, Buffenstein, Rochelle
Publié dans PLoS Biol (2019)

HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome

par Illing, Patricia T., Pymm, Phillip, Croft, Nathan P., Hilton, Hugo G., Jojic, Vladimir, Han, Alex S., Mendoza, Juan L., Mifsud, Nicole A., Dudek, Nadine L., McCluskey, James, Parham, Peter, Rossjohn, Jamie, Vivian, Julian P., Purcell, Anthony W.
Publié dans Nat Commun (2018)

High-resolution genetic and phenotypic analysis of KIR2DL1 alleles and their association with pre-eclampsia

par Huhn, Oisín, Chazara, Olympe, Ivarsson, Martin A., Retière, Christelle, Venkatesan, Tim, Norman, Paul J, Hilton, Hugo G, Jayaraman, Jyothi, Traherne, James A, Trowsdale, John, Ito, Mitsutero, Kling, Christiane, Parham, Peter, Ghadially, Hormas, Moffett, Ashley, Sharkey, Andrew M, Colucci, Francesco
Publié dans J Immunol (2018)

Different Selected Mechanisms Attenuated the Inhibitory Interaction of KIR2DL1 with C2(+) HLA-C in Two Indigenous Human Populations in Southern Africa ()

par Nemat-Gorgani, Neda, Hilton, Hugo G., Henn, Brenna M., Lin, Meng, Gignoux, Christopher R., Myrick, Justin W., Werely, Cedric J., Granka, Julie M., Möller, Marlo, Hoal, Eileen G., Yawata, Makoto, Yawata, Nobuyo, Boelen, Lies, Asquith, Becca, Parham, Peter, Norman, Paul J.
Publié dans J Immunol (2018)