Different Selected Mechanisms Attenuated the Inhibitory Interaction of KIR2DL1 with C2(+) HLA-C in Two Indigenous Human Populations in Southern Africa ()

The functions of human natural killer (NK) cells in defense against pathogens and placental development during reproduction are modulated by interactions of killer cell immunoglobulin-like receptors (KIR) with HLA-A, -B and -C class I ligands. Both receptors and ligands are highly polymorphic and ex...

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Publicado no:J Immunol
Main Authors: Nemat-Gorgani, Neda, Hilton, Hugo G., Henn, Brenna M., Lin, Meng, Gignoux, Christopher R., Myrick, Justin W., Werely, Cedric J., Granka, Julie M., Möller, Marlo, Hoal, Eileen G., Yawata, Makoto, Yawata, Nobuyo, Boelen, Lies, Asquith, Becca, Parham, Peter, Norman, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5990024/
https://ncbi.nlm.nih.gov/pubmed/29549179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701780
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