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Polymorphic HLA-C receptors balance the functional characteristics of KIR haplotypes

The human killer cell immunoglobulin-like receptor (KIR) locus comprises two groups of KIR haplotypes, termed A and B. These are present in all human populations but with different relative frequencies, suggesting they have different functional properties that underlie their balancing selection. We...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Hilton, Hugo G., Guethlein, Lisbeth A., Goyos, Ana, Nemat-Gorgani, Neda, Bushnell, David A., Norman, Paul J., Parham, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575877/
https://ncbi.nlm.nih.gov/pubmed/26311903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501358
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