KIR2DS5 allotypes that recognize the C2 epitope of HLA‐C are common among Africans and absent from Europeans

INTRODUCTION: KIR2DS5 is an activating human NK cell receptor of lineage III KIR. These include both inhibitory KIR2DL1, 2 and 3 and activating KIR2DS1 that recognize either the C1 or C2 epitope of HLA‐C. In Europeans KIR2DS5 is essentially monomorphic, with KIR2DS5*002 being predominant. Pioneering...

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Detalhes bibliográficos
Publicado no:Immun Inflamm Dis
Main Authors: Blokhuis, Jeroen H., Hilton, Hugo G., Guethlein, Lisbeth A., Norman, Paul J., Nemat‐Gorgani, Neda, Nakimuli, Annettee, Chazara, Olympe, Moffett, Ashley, Parham, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691316/
https://ncbi.nlm.nih.gov/pubmed/28685972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.178
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