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In vitro education of human natural killer cells by KIR3DL1

During development, NK cells are “educated” to respond aggressively to cells with low surface expression of HLA class I, a hallmark of malignant and infected cells. The mechanism of education involves interactions between inhibitory killer immunoglobulin–like receptors (KIRs) and specific HLA epitop...

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Détails bibliographiques
Publié dans:Life Sci Alliance
Auteurs principaux: Pugh, Jason, Nemat-Gorgani, Neda, Djaoud, Zakia, Guethlein, Lisbeth A, Norman, Paul J, Parham, Peter
Format: Artigo
Langue:Inglês
Publié: Life Science Alliance LLC 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6856763/
https://ncbi.nlm.nih.gov/pubmed/31723004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900434
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