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Human Natural Killer Cells Downregulate Zap70 and Syk in Response to Prolonged Activation or DNA Damage

The extent of NK cell activity during the innate immune response affects downstream immune functions and, ultimately, the outcome of infectious or malignant disease. However, the mechanisms that terminate human NK cell responses have yet to be defined. When activation receptors expressed on NK cell...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Pugh, Jason L., Nemat-Gorgani, Neda, Norman, Paul J., Guethlein, Lisbeth A., Parham, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5780205/
https://ncbi.nlm.nih.gov/pubmed/29263215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700542
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