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Human Natural Killer Cells Downregulate Zap70 and Syk in Response to Prolonged Activation or DNA Damage

The extent of NK cell activity during the innate immune response affects downstream immune functions and, ultimately, the outcome of infectious or malignant disease. However, the mechanisms that terminate human NK cell responses have yet to be defined. When activation receptors expressed on NK cell...

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Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Pugh, Jason L., Nemat-Gorgani, Neda, Norman, Paul J., Guethlein, Lisbeth A., Parham, Peter
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5780205/
https://ncbi.nlm.nih.gov/pubmed/29263215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700542
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