Loss and Gain of Natural Killer Cell Receptor Function in an African Hunter-Gatherer Population

Modulating natural killer cell functions in human immunity and reproduction are diverse interactions between the killer cell immunoglobulin-like receptors (KIR) of Natural Killer (NK) cells and HLA class I ligands on the surface of tissue cells. Dominant interactions are between KIR2DL1 and the C2 e...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Hilton, Hugo G., Norman, Paul J., Nemat-Gorgani, Neda, Goyos, Ana, Hollenbach, Jill A., Henn, Brenna M., Gignoux, Christopher R., Guethlein, Lisbeth A., Parham, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546388/
https://ncbi.nlm.nih.gov/pubmed/26292085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005439
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