Co-evolution of Human Leukocyte Antigen (HLA) Class I Ligands with Killer-Cell Immunoglobulin-Like Receptors (KIR) in a Genetically Diverse Population of Sub-Saharan Africans

Interactions between HLA class I molecules and killer-cell immunoglobulin-like receptors (KIR) control natural killer cell (NK) functions in immunity and reproduction. Encoded by genes on different chromosomes, these polymorphic ligands and receptors correlate highly with disease resistance and susc...

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Detalhes bibliográficos
Main Authors: Norman, Paul J., Hollenbach, Jill A., Nemat-Gorgani, Neda, Guethlein, Lisbeth A., Hilton, Hugo G., Pando, Marcelo J., Koram, Kwadwo A., Riley, Eleanor M., Abi-Rached, Laurent, Parham, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814319/
https://ncbi.nlm.nih.gov/pubmed/24204327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003938
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