Co-evolution of Human Leukocyte Antigen (HLA) Class I Ligands with Killer-Cell Immunoglobulin-Like Receptors (KIR) in a Genetically Diverse Population of Sub-Saharan Africans

Interactions between HLA class I molecules and killer-cell immunoglobulin-like receptors (KIR) control natural killer cell (NK) functions in immunity and reproduction. Encoded by genes on different chromosomes, these polymorphic ligands and receptors correlate highly with disease resistance and susc...

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Main Authors: Norman, Paul J., Hollenbach, Jill A., Nemat-Gorgani, Neda, Guethlein, Lisbeth A., Hilton, Hugo G., Pando, Marcelo J., Koram, Kwadwo A., Riley, Eleanor M., Abi-Rached, Laurent, Parham, Peter
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814319/
https://ncbi.nlm.nih.gov/pubmed/24204327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003938
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