CDK8 kinase activity promotes glycolysis

Por Galbraith, Matthew D., Andrysik, Zdenek, Pandey, Ahwan, Hoh, Maria, Bonner, Elizabeth A., Hill, Amanda A., Sullivan, Kelly D., Espinosa, Joaquín M.
Publicado no Cell Rep (2017)

Trisomy 21 consistently activates the interferon response

Por Sullivan, Kelly D, Lewis, Hannah C, Hill, Amanda A, Pandey, Ahwan, Jackson, Leisa P, Cabral, Joseph M, Smith, Keith P, Liggett, L Alexander, Gomez, Eliana B, Galbraith, Matthew D, DeGregori, James, Espinosa, Joaquín M
Publicado no eLife (2016)

Tyrosine kinase inhibition in leukemia induces an altered metabolic state sensitive to mitochondrial perturbations

Por Alvarez-Calderon, Francesca, Gregory, Mark A., Pham-Danis, Catherine, DeRyckere, Deborah, Stevens, Brett M., Zaberezhnyy, Vadym, Hill, Amanda A., Gemta, Lelisa, Kumar, Amit, Kumar, Vijay, Wempe, Michael F., Pollyea, Daniel A., Jordan, Craig T., Serkova, Natalie J., Graham, Douglas K., DeGregori, James
Publicado no Clin Cancer Res (2014)

Efficacy of a Mer and Flt3 tyrosine kinase small molecule inhibitor, UNC1666, in acute myeloid leukemia

Por Lee-Sherick, Alisa B., Zhang, Weihe, Menachof, Kelly K., Hill, Amanda A., Rinella, Sean, Kirkpatrick, Gregory, Page, Lauren S., Stashko, Michael A., Jordan, Craig T., Wei, Qi, Liu, Jing, Zhang, Dehui, DeRyckere, Deborah, Wang, Xiaodong, Frye, Stephen, Earp, H. Shelton, Graham, Douglas K.
Publicado no Oncotarget (2015)

UNC2025, a MERTK small molecule inhibitor, is therapeutically effective alone and in combination with methotrexate in leukemia models

Por DeRyckere, Deborah, Lee-Sherick, Alisa B., Huey, Madeline G., Hill, Amanda A., Tyner, Jeffrey W., Jacobsen, Kristen M., Page, Lauren S., Kirkpatrick, Gregory G., Eryildiz, Fatma, Montgomery, Stephanie A., Zhang, Weihe, Wang, Xiaodong, Frye, Stephen V., Earp, H. Shelton, Graham, Douglas K.
Publicado no Clin Cancer Res (2016)