Efficacy of a Mer and Flt3 tyrosine kinase small molecule inhibitor, UNC1666, in acute myeloid leukemia

Mer and Flt3 receptor tyrosine kinases have been implicated as therapeutic targets in acute myeloid leukemia (AML). In this manuscript we describe UNC1666, a novel ATP-competitive small molecule tyrosine kinase inhibitor, which potently diminishes Mer and Flt3 phosphorylation in AML. Treatment with...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lee-Sherick, Alisa B., Zhang, Weihe, Menachof, Kelly K., Hill, Amanda A., Rinella, Sean, Kirkpatrick, Gregory, Page, Lauren S., Stashko, Michael A., Jordan, Craig T., Wei, Qi, Liu, Jing, Zhang, Dehui, DeRyckere, Deborah, Wang, Xiaodong, Frye, Stephen, Earp, H. Shelton, Graham, Douglas K.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466645/
https://ncbi.nlm.nih.gov/pubmed/25762638
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados