UNC1062, a new and potent Mer inhibitor

Abnormal activation of Mer kinase has been implicated in the oncogenesis of many human cancers including acute lymphoblastic and myeloid leukemia, non-small cell lung cancer, and glioblastoma. We have discovered a new family of small molecule Mer inhibitors, pyrazolopyrimidine sulfonamides, that pot...

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Detalhes bibliográficos
Main Authors: Liu, Jing, Zhang, Weihe, Stashko, Michael A, DeRyckere, Deborah, Cummings, Christopher T., Hunter, Debra, Yang, Chao, Jayakody, Chatura N., Cheng, Nancy, Simpson, Catherine, Norris-Drouin, Jacqueline, Sather, Susan, Kireev, Dmitri, Janzen, William P., Earp, H Shelton, Graham, Douglas K., Frye, Stephen V., Wang, Xiaodong
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720808/
https://ncbi.nlm.nih.gov/pubmed/23693152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2013.03.035
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