UNC569, a novel small molecule Mer inhibitor with efficacy against acute lymphoblastic leukemia in vitro and in vivo

Acute lymphoblastic leukemia (ALL) is the most common malignancy in children. Although survival rates have improved, patients with certain biological subtypes still have suboptimal outcomes. Current chemotherapeutic regimens are associated with short- and long-term toxicities and novel, less toxic t...

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Main Authors: Christoph, Sandra, DeRyckere, Deborah, Schlegel, Jennifer, Frazer, J. Kimble, Batchelor, Lance A., Trakhimets, Alesia Y., Sather, Susan, Hunter, Debra M., Cummings, Christopher, Liu, Jing, Yang, Chao, Kireev, Dmitri, Simpson, Catherine, Norris-Drouin, Jacqueline, Hull-Ryde, Emily A., Janzen, William P., Johnson, Gary L., Wang, Xiaodong, Frye, Stephen V., Earp, H. Shelton, Graham, Douglas K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823742/
https://ncbi.nlm.nih.gov/pubmed/23997116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0040
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