Design and Synthesis of Novel Macrocyclic Mer Tyrosine Kinase Inhibitors

[Image: see text] Mer tyrosine kinase (MerTK) is aberrantly elevated in various tumor cells and has a normal anti-inflammatory role in the innate immune system. Inhibition of MerTK may provide dual effects against these MerTK-expressing tumors through reducing cancer cell survival and redirecting th...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Wang, Xiaodong, Liu, Jing, Zhang, Weihe, Stashko, Michael A., Nichols, James, Miley, Michael J., Norris-Drouin, Jacqueline, Chen, Zhilong, Machius, Mischa, DeRyckere, Deborah, Wood, Edgar, Graham, Douglas K., Earp, H. Shelton, Kireev, Dmitri, Frye, Stephen V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5151143/
https://ncbi.nlm.nih.gov/pubmed/27994735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00221
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados