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CDK8 kinase activity promotes glycolysis

Aerobic glycolysis, also known as the Warburg effect, is a hallmark of cancerous tissues. Despite its importance in cancer development, our understanding of mechanisms driving this form of metabolic reprogramming is incomplete. We report here an analysis of colorectal cancer cells engineered to carr...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Galbraith, Matthew D., Andrysik, Zdenek, Pandey, Ahwan, Hoh, Maria, Bonner, Elizabeth A., Hill, Amanda A., Sullivan, Kelly D., Espinosa, Joaquín M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726794/
https://ncbi.nlm.nih.gov/pubmed/29117556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.10.058
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