IQGAPs choreograph cellular signaling from the membrane to the nucleus

Por Smith, Jessica M., Hedman, Andrew C., Sacks, David B.
Publicado no Trends Cell Biol (2015)

The biology of IQGAP proteins: beyond the cytoskeleton

Por Hedman, Andrew C, Smith, Jessica M, Sacks, David B
Publicado no EMBO Rep (2015)

An unexpected role for PI4,5P(2) in EGF receptor endosomal trafficking

Por Sun, Yue, Hedman, Andrew C., Tan, Xiaojun, Anderson, Richard A.
Publicado em 2013

Phosphatidylinositol-4,5-bisphosphate: Targeted Production and Signaling

Por Sun, Yue, Thapa, Narendra, Hedman, Andrew C., Anderson, Richard A.
Publicado em 2013

Isoform 5 of PIPKIγ regulates the endosomal trafficking and degradation of E-cadherin

Por Schill, Nicholas J., Hedman, Andrew C., Choi, Suyong, Anderson, Richard A.
Publicado em 2014

PIP kinases define PI4,5P(2) signaling specificity by association with effectors

Por Choi, Suyong, Thapa, Narendra, Tan, Xiaojun, Hedman, Andrew C., Anderson, Richard A.
Publicado no Biochim Biophys Acta (2015)

Endosomal Type Iγ PIP 5-Kinase Controls EGF Receptor Lysosomal Sorting

Por Sun, Yue, Hedman, Andrew C., Tan, Xiaojun, Schill, Nicholas J., Anderson, Richard A.
Publicado em 2013

IQGAP1 Binds to Yes-associated Protein (YAP) and Modulates Its Transcriptional Activity

Por Sayedyahossein, Samar, Li, Zhigang, Hedman, Andrew C., Morgan, Chase J., Sacks, David B.
Publicado no J Biol Chem (2016)

Calmodulin Lobes Facilitate Dimerization and Activation of Estrogen Receptor-α

Por Li, Zhigang, Zhang, Yonghong, Hedman, Andrew C., Ames, James B., Sacks, David B.
Publicado no J Biol Chem (2017)

LAPTM4B is a PtdIns(4,5)P(2) effector that regulates EGFR signaling, lysosomal sorting, and degradation

Por Tan, Xiaojun, Sun, Yue, Thapa, Narendra, Liao, Yihan, Hedman, Andrew C, Anderson, Richard A
Publicado no EMBO J (2015)

IQGAP1 is a novel phosphatidylinositol 4,5 bisphosphate effector in regulation of directional cell migration

Por Choi, Suyong, Thapa, Narendra, Hedman, Andrew C, Li, Zhigang, Sacks, David B, Anderson, Richard A
Publicado em 2013

Absence of IQGAP1 Protein Leads to Insulin Resistance

Por Chawla, Bhavna, Hedman, Andrew C., Sayedyahossein, Samar, Erdemir, Huseyin H., Li, Zhigang, Sacks, David B.
Publicado no J Biol Chem (2017)

Agonist-stimulated phosphatidylinositol-3,4,5-trisphosphate generation by scaffolded phosphoinositide kinases

Por Choi, Suyong, Hedman, Andrew C., Sayedyahossein, Samar, Thapa, Narendra, Sacks, David B., Anderson, Richard A.
Publicado no Nat Cell Biol (2016)