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Calmodulin Lobes Facilitate Dimerization and Activation of Estrogen Receptor-α
Estrogen receptor α (ER-α) is a nuclear hormone receptor that controls selected genes, thereby regulating proliferation and differentiation of target tissues, such as breast. Gene expression controlled by ER-α is modulated by Ca(2+) via calmodulin (CaM). Here we present the NMR structure of Ca(2+)-C...
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| 發表在: | J Biol Chem |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5377777/ https://ncbi.nlm.nih.gov/pubmed/28174300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.754804 |
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