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Endosomal Type Iγ PIP 5-Kinase Controls EGF Receptor Lysosomal Sorting
Endosomal trafficking and degradation of epidermal growth factor receptor (EGFR) play an essential role in control of its signaling. Phosphatidylinositol-4,5-bisphosphate (PtdIns4,5P(2)) is an established regulator of endocytosis, whereas PtdIns3P modulates endosomal trafficking. However, here we de...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3740164/ https://ncbi.nlm.nih.gov/pubmed/23602387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.03.010 |
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