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Endosomal Type Iγ PIP 5-Kinase Controls EGF Receptor Lysosomal Sorting

Endosomal trafficking and degradation of epidermal growth factor receptor (EGFR) play an essential role in control of its signaling. Phosphatidylinositol-4,5-bisphosphate (PtdIns4,5P(2)) is an established regulator of endocytosis, whereas PtdIns3P modulates endosomal trafficking. However, here we de...

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Autors principals: Sun, Yue, Hedman, Andrew C., Tan, Xiaojun, Schill, Nicholas J., Anderson, Richard A.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740164/
https://ncbi.nlm.nih.gov/pubmed/23602387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.03.010
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