Učitavanje...
Absence of IQGAP1 Protein Leads to Insulin Resistance
Insulin binds to the insulin receptor (IR) and induces tyrosine phosphorylation of the receptor and insulin receptor substrate-1 (IRS-1), leading to activation of the PKB/Akt and MAPK/ERK pathways. IQGAP1 is a scaffold protein that interacts with multiple binding partners and integrates diverse sign...
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| Izdano u: | J Biol Chem |
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| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5336162/ https://ncbi.nlm.nih.gov/pubmed/28082684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.752642 |
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