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IQGAPs choreograph cellular signaling from the membrane to the nucleus

Since its discovery in 1994, cellular functions for the scaffold protein IQGAP1 have expanded immensely. Over 100 unique IQGAP1 interacting proteins have been identified, implicating IQGAP1 as a critical integrator of cellular signaling pathways. Initial research established functions for IQGAP1 in...

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Veröffentlicht in:Trends Cell Biol
Hauptverfasser: Smith, Jessica M., Hedman, Andrew C., Sacks, David B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344846/
https://ncbi.nlm.nih.gov/pubmed/25618329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2014.12.005
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