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IQGAP1 binds AMPK and is required for maximum AMPK activation

AMP-activated protein kinase (AMPK) is a fundamental component of a protein kinase cascade that is an energy sensor. AMPK maintains energy homeostasis in the cell by promoting catabolic and inhibiting anabolic pathways. Activation of AMPK requires phosphorylation by the liver kinase B1 or by the Ca(...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Hedman, Andrew C., Li, Zhigang, Gorisse, Laëtitia, Parvathaneni, Swetha, Morgan, Chase J., Sacks, David B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948462/
https://ncbi.nlm.nih.gov/pubmed/33191271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.016193
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