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IQGAP1 modulates activation of B-Raf

IQGAP1 modulates several cellular functions, including cell–cell adhesion, transcription, cytoskeletal architecture, and selected signaling pathways. We previously documented that IQGAP1 binds ERK and MAPK kinase (MEK) and regulates EGF-stimulated MEK and ERK activity. Here we characterize the inter...

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Detalhes bibliográficos
Main Authors: Ren, Jian-Guo, Li, Zhigang, Sacks, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1965536/
https://ncbi.nlm.nih.gov/pubmed/17563371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611308104
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