IQGAP1 binds AMPK and is required for maximum AMPK activation

AMP-activated protein kinase (AMPK) is a fundamental component of a protein kinase cascade that is an energy sensor. AMPK maintains energy homeostasis in the cell by promoting catabolic and inhibiting anabolic pathways. Activation of AMPK requires phosphorylation by the liver kinase B1 or by the Ca(...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Hedman, Andrew C., Li, Zhigang, Gorisse, Laëtitia, Parvathaneni, Swetha, Morgan, Chase J., Sacks, David B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948462/
https://ncbi.nlm.nih.gov/pubmed/33191271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.016193
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