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IQGAPs choreograph cellular signaling from the membrane to the nucleus

Since its discovery in 1994, cellular functions for the scaffold protein IQGAP1 have expanded immensely. Over 100 unique IQGAP1 interacting proteins have been identified, implicating IQGAP1 as a critical integrator of cellular signaling pathways. Initial research established functions for IQGAP1 in...

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Publicado en:Trends Cell Biol
Main Authors: Smith, Jessica M., Hedman, Andrew C., Sacks, David B.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344846/
https://ncbi.nlm.nih.gov/pubmed/25618329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2014.12.005
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