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IQGAP1 is a novel phosphatidylinositol 4,5 bisphosphate effector in regulation of directional cell migration

Phosphatidylinositol 4,5 bisphosphate (PIP(2)) is a key lipid messenger for regulation of cell migration. PIP(2) modulates many effectors, but the specificity of PIP(2) signalling can be defined by interactions of PIP(2)-generating enzymes with PIP(2) effectors. Here, we show that type Iγ phosphatid...

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Detalhes bibliográficos
Main Authors: Choi, Suyong, Thapa, Narendra, Hedman, Andrew C, Li, Zhigang, Sacks, David B, Anderson, Richard A
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791370/
https://ncbi.nlm.nih.gov/pubmed/23982733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.191
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