Comparative methylomics reveals gene-body H3K36me3 in Drosophila predicts DNA methylation and CpG landscapes in other invertebrates

gan Nanty, Lisa, Carbajosa, Guillermo, Heap, Graham A., Ratnieks, Francis, van Heel, David A., Down, Thomas A., Rakyan, Vardhman K.
Cyhoeddwyd 2011

Complex nature of SNP genotype effects on gene expression in primary human leucocytes

gan Heap, Graham A, Trynka, Gosia, Jansen, Ritsert C, Bruinenberg, Marcel, Swertz, Morris A, Dinesen, Lotte C, Hunt, Karen A, Wijmenga, Cisca, vanHeel, David A, Franke, Lude
Cyhoeddwyd 2009

Shared and Distinct Genetic Variants in Type 1 Diabetes and Celiac Disease

gan Smyth, Deborah J, Plagnol, Vincent, Walker, Neil M, Cooper, Jason D, Downes, Kate, Yang, Jennie HM, Howson, Joanna MM, Stevens, Helen, McManus, Ross, Wijmenga, Cisca, Heap, Graham A., Dubois, Patrick C., Clayton, David G., Hunt, Karen A, van Heel, David A, Todd, John A
Cyhoeddwyd 2008

Genome-wide analysis of allelic expression imbalance in human primary cells by high-throughput transcriptome resequencing

gan Heap, Graham A., Yang, Jennie H.M., Downes, Kate, Healy, Barry C., Hunt, Karen A., Bockett, Nicholas, Franke, Lude, Dubois, Patrick C., Mein, Charles A., Dobson, Richard J., Albert, Thomas J., Rodesch, Matthew J., Clayton, David G., Todd, John A., van Heel, David A., Plagnol, Vincent
Cyhoeddwyd 2010

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease

gan de Lange, Katrina M., Moutsianas, Loukas, Lee, James C., Lamb, Christopher A., Luo, Yang, Kennedy, Nicholas A., Jostins, Luke, Rice, Daniel L., Gutierrez-Achury, Javier, Ji, Sun-Gou, Heap, Graham, Nimmo, Elaine R., Edwards, Cathryn, Henderson, Paul, Mowat, Craig, Sanderson, Jeremy, Satsangi, Jack, Simmons, Alison, Wilson, David C., Tremelling, Mark, Hart, Ailsa, Mathew, Christopher G., Newman, William G., Parkes, Miles, Lees, Charlie W., Uhlig, Holm, Hawkey, Chris, Prescott, Natalie J., Ahmad, Tariq, Mansfield, John C., Anderson, Carl A., Barrett, Jeffrey C.
Cyhoeddwyd yn Nat Genet (2017)

Novel celiac disease genetic determinants related to the immune response

gan Hunt, Karen A, Zhernakova, Alexandra, Turner, Graham, Heap, Graham A.R., Franke, Lude, Bruinenberg, Marcel, Romanos, Jihane, Dinesen, Lotte C., Ryan, Anthony W, Panesar, Davinder, Gwilliam, Rhian, Takeuchi, Fumihiko, McLaren, William M, Holmes, Geoffrey KT, Howdle, Peter D, Walters, Julian RF, Sanders, David S, Playford, Raymond J, Trynka, Gosia, Mulder, Chris JJ, Mearin, M Luisa, Verbeek, Wieke HM, Trimble, Valerie, Stevens, Fiona M, O’Morain, Colm, Kennedy, Nicholas P, Kelleher, Dermot, Pennington, Daniel J, Strachan, David P, McArdle, Wendy L, Mein, Charles A, Wapenaar, Martin C, Deloukas, Panos, McGinnis, Ralph, McManus, Ross, Wijmenga, Cisca, van Heel, David A
Cyhoeddwyd 2008

Erratum: A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis

gan Rivas, Manuel A., Graham, Daniel, Sulem, Patrick, Stevens, Christine, Desch, A. Nicole, Goyette, Philippe, Gudbjartsson, Daniel, Jonsdottir, Ingileif, Thorsteinsdottir, Unnur, Degenhardt, Frauke, Mucha, Sören, Kurki, Mitja I., Li, Dalin, D'Amato, Mauro, Annese, Vito, Vermeire, Severine, Weersma, Rinse K., Halfvarson, Jonas, Paavola-Sakki, Paulina, Lappalainen, Maarit, Lek, Monkol, Cummings, Beryl, Tukiainen, Taru, Haritunians, Talin, Halme, Leena, Koskinen, Lotta L. E., Ananthakrishnan, Ashwin N., Luo, Yang, Heap, Graham A., Visschedijk, Marijn C., MacArthur, Daniel G., Neale, Benjamin M., Ahmad, Tariq, Anderson, Carl A., Brant, Steven R., Duerr, Richard H., Silverberg, Mark S., Cho, Judy H., Palotie, Aarno, Saavalainen, Päivi, Kontula, Kimmo, Färkkilä, Martti, McGovern, Dermot P. B., Franke, Andre, Stefansson, Kari, Rioux, John D., Xavier, Ramnik J., Daly, Mark J.
Cyhoeddwyd yn Nat Commun (2016)

Association of Genetic Variants in NUDT15 With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease

gan Walker, Gareth J., Harrison, James W., Heap, Graham A., Voskuil, Michiel D., Andersen, Vibeke, Anderson, Carl A., Ananthakrishnan, Ashwin N., Barrett, Jeffrey C., Beaugerie, Laurent, Bewshea, Claire M., Cole, Andy T., Cummings, Fraser R., Daly, Mark J., Ellul, Pierre, Fedorak, Richard N., Festen, Eleonora A. M., Florin, Timothy H., Gaya, Daniel R., Halfvarson, Jonas, Hart, Ailsa L., Heerasing, Neel M., Hendy, Peter, Irving, Peter M., Jones, Samuel E., Koskela, Jukka, Lindsay, James O., Mansfield, John C., McGovern, Dermot, Parkes, Miles, Pollok, Richard C. G., Ramakrishnan, Subramaniam, Rampton, David S., Rivas, Manuel A., Russell, Richard K., Schultz, Michael, Sebastian, Shaji, Seksik, Philippe, Singh, Abhey, So, Kenji, Sokol, Harry, Subramaniam, Kavitha, Todd, Anthony, Annese, Vito, Weersma, Rinse K., Xavier, Ramnik, Ward, Rebecca, Weedon, Michael N., Goodhand, James R., Kennedy, Nicholas A., Ahmad, Tariq
Cyhoeddwyd yn JAMA (2019)

Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population

gan Rivas, Manuel A., Avila, Brandon E., Koskela, Jukka, Huang, Hailiang, Stevens, Christine, Pirinen, Matti, Haritunians, Talin, Neale, Benjamin M., Kurki, Mitja, Ganna, Andrea, Graham, Daniel, Glaser, Benjamin, Peter, Inga, Atzmon, Gil, Barzilai, Nir, Levine, Adam P., Schiff, Elena, Pontikos, Nikolas, Weisburd, Ben, Lek, Monkol, Karczewski, Konrad J., Bloom, Jonathan, Minikel, Eric V., Petersen, Britt-Sabina, Beaugerie, Laurent, Seksik, Philippe, Cosnes, Jacques, Schreiber, Stefan, Bokemeyer, Bernd, Bethge, Johannes, Heap, Graham, Ahmad, Tariq, Plagnol, Vincent, Segal, Anthony W., Targan, Stephan, Turner, Dan, Saavalainen, Paivi, Farkkila, Martti, Kontula, Kimmo, Palotie, Aarno, Brant, Steven R., Duerr, Richard H., Silverberg, Mark S., Rioux, John D., Weersma, Rinse K., Franke, Andre, Jostins, Luke, Anderson, Carl A., Barrett, Jeffrey C., MacArthur, Daniel G., Jalas, Chaim, Sokol, Harry, Xavier, Ramnik J., Pulver, Ann, Cho, Judy H., McGovern, Dermot P. B., Daly, Mark J.
Cyhoeddwyd yn PLoS Genet (2018)

HLA-DQA1-HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants

gan Heap, Graham A, Weedon, Michael N, Bewshea, Claire M, Singh, Abhey, Chen, Mian, Satchwell, Jack B, Vivian, Julian P, So, Kenji, Dubois, Patrick C, Andrews, Jane M, Annese, Vito, Bampton, Peter, Barnardo, Martin, Bell, Sally, Cole, Andy, Connor, Susan J, Creed, Tom, Cummings, Fraser R, D'Amato, Mauro, Daneshmend, Tawfique K, Fedorak, Richard N, Florin, Timothy H, Gaya, Daniel R, Greig, Emma, Halfvarson, Jonas, Hart, Alisa, Irving, Peter M, Jones, Gareth, Karban, Amir, Lawrance, Ian C, Lee, James C, Lees, Charlie, Lev-Tzion, Raffi, Lindsay, James O, Mansfield, John, Mawdsley, Joel, Mazhar, Zia, Parkes, Miles, Parnell, Kirstie, Orchard, Timothy R, Radford-Smith, Graham, Russell, Richard K, Reffitt, David, Satsangi, Jack, Silverberg, Mark S, Sturniolo, Giacomo C, Tremelling, Mark, Tsianos, Epameinondas V, van Heel, David A, Walsh, Alissa, Watermeyer, Gill, Weersma, Rinse K, Zeissig, Sebastian, Rossjohn, Jamie, Holden, Arthur L, Ahmad, Tariq
Cyhoeddwyd yn Nat Genet (2014)

Correction: Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population

gan Rivas, Manuel A., Avila, Brandon E., Koskela, Jukka, Huang, Hailiang, Stevens, Christine, Pirinen, Matti, Haritunians, Talin, Neale, Benjamin M., Kurki, Mitja, Ganna, Andrea, Graham, Daniel, Glaser, Benjamin, Peter, Inga, Atzmon, Gil, Barzilai, Nir, Levine, Adam P., Schiff, Elena, Pontikos, Nikolas, Weisburd, Ben, Lek, Monkol, Karczewski, Konrad J., Bloom, Jonathan, Minikel, Eric V., Petersen, Britt-Sabina, Beaugerie, Laurent, Seksik, Philippe, Cosnes, Jacques, Schreiber, Stefan, Bokemeyer, Bernd, Bethge, Johannes, Heap, Graham, Ahmad, Tariq, Plagnol, Vincent, Segal, Anthony W., Targan, Stephan, Turner, Dan, Saavalainen, Paivi, Farkkila, Martti, Kontula, Kimmo, Palotie, Aarno, Brant, Steven R., Duerr, Richard H., Silverberg, Mark S., Rioux, John D., Weersma, Rinse K., Franke, Andre, Jostins, Luke, Anderson, Carl A., Barrett, Jeffrey C., MacArthur, Daniel G., Jalas, Chaim, Sokol, Harry, Xavier, Ramnik J., Pulver, Ann, Cho, Judy H., McGovern, Dermot P. B., Daly, Mark J.
Cyhoeddwyd yn PLoS Genet (2019)

Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

gan Trynka, Gosia, Hunt, Karen A, Bockett, Nicholas A, Romanos, Jihane, Mistry, Vanisha, Szperl, Agata, Bakker, Sjoerd F, Bardella, Maria Teresa, Bhaw-Rosun, Leena, Castillejo, Gemma, de la Concha, Emilio G., de Almeida, Rodrigo Coutinho, Dias, Kerith-Rae M, van Diemen, Cleo C., Dubois, Patrick CA, Duerr, Richard H., Edkins, Sarah, Franke, Lude, Fransen, Karin, Gutierrez, Javier, Heap, Graham AR, Hrdlickova, Barbara, Hunt, Sarah, Izurieta, Leticia Plaza, Izzo, Valentina, Joosten, Leo AB, Langford, Cordelia, Mazzilli, Maria Cristina, Mein, Charles A, Midah, Vandana, Mitrovic, Mitja, Mora, Barbara, Morelli, Marinita, Nutland, Sarah, Núñez, Concepción, Onengut-Gumuscu, Suna, Pearce, Kerra, Platteel, Mathieu, Polanco, Isabel, Potter, Simon, Ribes-Koninckx, Carmen, Ricaño-Ponce, Isis, Rich, Stephen S., Rybak, Anna, Santiago, José Luis, Senapati, Sabyasachi, Sood, Ajit, Szajewska, Hania, Troncone, Riccardo, Varadé, Jezabel, Wallace, Chris, Wolters, Victorien M, Zhernakova, Alexandra, Thelma, B.K., Cukrowska, Bozena, Urcelay, Elena, Bilbao, Jose Ramon, Mearin, M Luisa, Barisani, Donatella, Barrett, Jeffrey C, Plagnol, Vincent, Deloukas, Panos, Wijmenga, Cisca, van Heel, David A
Cyhoeddwyd 2011

Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry

gan Hunt, Karen A, Smyth, Deborah J, Balschun, Tobias, Ban, Maria, Mistry, Vanisha, Ahmed, Tariq, Anand, Vidya, Barrett, Jeffrey C, Bhaw-Rosun, Leena, Bockett, Nicholas A, Brand, Oliver J, Brouwer, Elisabeth, Concannon, Patrick, Cooper, Jason D, Dias, Kerith-Rae M, van Diemen, Cleo C, Dubois, Patrick C, Edkins, Sarah, Fölster-Holst, Regina, Fransen, Karin, Glass, David N., Heap, Graham AR, Hofmann, Sylvia, Huizinga, Tom WJ, Hunt, Sarah, Langford, Cordelia, Lee, James, Mansfield, John, Marrosu, Maria Giovanna, Mathew, Christopher G, Mein, Charles A, Müller-Quernheim, Joachim, Nutland, Sarah, Onengut-Gumuscu, Suna, Ouwehand, Willem, Pearce, Kerra, Prescott, Natalie, Posthumus, Marcel D, Potter, Simon, Rosati, Giulio, Sambrook, Jennifer, Satsangi, Jack, Schreiber, Stefan, Shtir, Corina, Simmonds, Matthew J, Sudman, Marc, Thompson, Susan D, Toes, Rene, Trynka, Gosia, Vyse, Timothy J, Walker, Neil M, Weidinger, Stephan, Zhernakova, Alexandra, Zoledziewska, Magdalena, Weersma, Rinse K, Gough, Stephen CL, Sawcer, Stephen, Wijmenga, Cisca, Parkes, Miles, Cucca, Francesco, Franke, Andre, Deloukas, Panos, Rich, Stephen S., Todd, John A, van Heel, David A
Cyhoeddwyd 2011

Multiple common variants for celiac disease influencing immune gene expression

gan Dubois, Patrick CA, Trynka, Gosia, Franke, Lude, Hunt, Karen A, Romanos, Jihane, Curtotti, Alessandra, Zhernakova, Alexandra, Heap, Graham AR, Ádány, Róza, Aromaa, Arpo, Bardella, Maria Teresa, van den Berg, Leonard H, Bockett, Nicholas A, de la Concha, Emilio G., Dema, Bárbara, Fehrmann, Rudolf SN, Fernández-Arquero, Miguel, Fiatal, Szilvia, Grandone, Elvira, Green, Peter M, Groen, Harry JM, Gwilliam, Rhian, Houwen, Roderick HJ, Hunt, Sarah E, Kaukinen, Katri, Kelleher, Dermot, Korponay-Szabo, Ilma, Kurppa, Kalle, MacMathuna, Padraic, Mäki, Markku, Mazzilli, Maria Cristina, McCann, Owen T, Mearin, M Luisa, Mein, Charles A, Mirza, Muddassar M, Mistry, Vanisha, Mora, Barbara, Morley, Katherine I, Mulder, Chris J, Murray, Joseph A, Núñez, Concepción, Oosterom, Elvira, Ophoff, Roel A, Polanco, Isabel, Peltonen, Leena, Platteel, Mathieu, Rybak, Anna, Salomaa, Veikko, Schweizer, Joachim J, Sperandeo, Maria Pia, Tack, Greetje J, Turner, Graham, Veldink, Jan H, Verbeek, Wieke HM, Weersma, Rinse K, Wolters, Victorien M, Urcelay, Elena, Cukrowska, Bozena, Greco, Luigi, Neuhausen, Susan L., McManus, Ross, Barisani, Donatella, Deloukas, Panos, Barrett, Jeffrey C, Saavalainen, Paivi, Wijmenga, Cisca, van Heel, David A
Cyhoeddwyd 2010

A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis

gan Rivas, Manuel A., Graham, Daniel, Sulem, Patrick, Stevens, Christine, Desch, A. Nicole, Goyette, Philippe, Gudbjartsson, Daniel, Jonsdottir, Ingileif, Thorsteinsdottir, Unnur, Degenhardt, Frauke, Mucha, Sören, Kurki, Mitja I., Li, Dalin, D'Amato, Mauro, Annese, Vito, Vermeire, Severine, Weersma, Rinse K., Halfvarson, Jonas, Paavola-Sakki, Paulina, Lappalainen, Maarit, Lek, Monkol, Cummings, Beryl, Tukiainen, Taru, Haritunians, Talin, Halme, Leena, Koskinen, Lotta L. E., Ananthakrishnan, Ashwin N., Luo, Yang, Heap, Graham A., Visschedijk, Marijn C., MacArthur, Daniel G., Neale, Benjamin M., Ahmad, Tariq, Anderson, Carl A., Brant, Steven R., Duerr, Richard H., Silverberg, Mark S., Cho, Judy H, Palotie, Aarno, Saavalainen, Päivi, Kontula, Kimmo, Färkkilä, Martti, McGovern, Dermot P. B., Franke, Andre, Stefansson, Kari, Rioux, John D., Xavier, Ramnik J., Daly, Mark J., Barrett, J., de Lane, K., Edwards, C., Hart, A., Hawkey, C., Jostins, L., Kennedy, N., Lamb, C., Lee, J., Lees, C., Mansfield, J., Mathew, C., Mowatt, C., Newman, B., Nimmo, E., Parkes, M., Pollard, M., Prescott, N., Randall, J., Rice, D., Satsangi, J., Simmons, A., Tremelling, M., Uhlig, H., Wilson, D., Abraham, C., Achkar, J. P., Bitton, A., Boucher, G., Croitoru, K., Fleshner, P., Glas, J., Kugathasan, S., Limbergen, J. V., Milgrom, R., Proctor, D., Regueiro, M., Schumm, P. L., Sharma, Y., Stempak, J. M., Targan, S. R., Wang, M. H.
Cyhoeddwyd yn Nat Commun (2016)