Paneth Cell Alterations in the Development and Phenotype of Crohn’s Disease

Por Stappenbeck, Thaddeus S., McGovern, Dermot P.B.
Publicado no Gastroenterology (2016)

Genetic variation in IBD: progress, clues to pathogenesis and possible clinical utility

Por Ye, Byong Duk, McGovern, Dermot P.B.
Publicado no Expert Rev Clin Immunol (2016)

Spatial and Temporal Stability of Paneth Cell Phenotypes in Crohn’s Disease: Implications for Prognostic Cellular Biomarker Development

Por Liu, Ta-Chiang, Gao, Feng, McGovern, Dermot P. B., Stappenbeck, Thaddeus S.
Publicado em 2014

Multilevel regularized regression for simultaneous taxa selection and network construction with metagenomic count data

Por Liu, Zhenqiu, Sun, Fengzhu, Braun, Jonathan, McGovern, Dermot P.B., Piantadosi, Steven
Publicado no Bioinformatics (2015)

Further Evidence of IBD5/CARD15 (NOD2) Epistasis in the Susceptibility to Ulcerative Colitis

Por McGovern, Dermot P. B., van Heel, David A., Negoro, Kenichi, Ahmad, Tariq, Jewell, Derek P.
Publicado em 2003

Distinct IFNG Methylation in a Subset of Ulcerative Colitis Patients Based upon Reactivity to Microbial Antigens

Por Gonsky, Rivkah, Deem, Richard L, Landers, Carol J, Derkowski, Carrie A, Berel, Dror, McGovern, Dermot P B, Targan, Stephan R
Publicado em 2011

Microbial, metabolomic, and immunologic dynamics in a relapsing genetic mouse model of colitis induced by T-synthase deficiency

Por Jacobs, Jonathan P., Lin, Lin, Goudarzi, Maryam, Ruegger, Paul, McGovern, Dermot P. B., Fornace, Albert J., Borneman, James, Xia, Lijun, Braun, Jonathan
Publicado no Gut Microbes (2016)

IBD-Associated TL1A Gene (TNFSF15) Haplotypes Determine Increased Expression of TL1A Protein

Por Michelsen, Kathrin S., Thomas, Lisa S., Taylor, Kent D., Yu, Qi T., Mei, Ling, Landers, Carol J., Derkowski, Carrie, McGovern, Dermot P. B., Rotter, Jerome I., Targan, Stephan R.
Publicado em 2009

Association of NOD2 and IL23R with Inflammatory Bowel Disease in Puerto Rico

Por Ballester, Veroushka, Guo, Xiuqing, Vendrell, Roberto, Haritunians, Talin, Klomhaus, Alexandra M., Li, Dalin, McGovern, Dermot P. B., Rotter, Jerome I., Torres, Esther A., Taylor, Kent D.
Publicado em 2014

Increased prevalence of inflammatory bowel disease in patients with mutations in genes encoding the receptor subunits for TGFβ

Por Guerrerio, Anthony L., Frischmeyer-Guerrerio, Pamela A., Huang, Chengrui, Wu, Yuqiong, Haritunians, Talin, McGovern, Dermot P.B., MacCarrick, Gretchen L., Brant, Steven R., Dietz, Harry C.
Publicado no Inflamm Bowel Dis (2016)

Pyoderma gangrenosum among patients with inflammatory bowel disease: a descriptive cohort study

Por Weizman, Adam V., Huang, Brian, Targan, Stephan, Dubinsky, Marla, Fleshner, Phillip, Kaur, Manreet, Ippoliti, Andrew, Panikkath, Deepa, Vasiliauskas, Eric, Shih, David, McGovern, Dermot P.B., Melmed, Gil Y.
Publicado no J Cutan Med Surg (2014)

A Modular Organization of the Human Intestinal Mucosal Microbiota and Its Association with Inflammatory Bowel Disease

Por Tong, Maomeng, Li, Xiaoxiao, Wegener Parfrey, Laura, Roth, Bennett, Ippoliti, Andrew, Wei, Bo, Borneman, James, McGovern, Dermot P. B., Frank, Daniel N., Li, Ellen, Horvath, Steve, Knight, Rob, Braun, Jonathan
Publicado em 2013

Human Natural Killer Cells Licensed by KIR Genes Have an Altered Cytokine Program That Modifies CD4(+) T Cell Function()

Por Lin, Lin, Ma, Chao, Wei, Bo, Aziz, Najib, Rajalingam, Raja, Yusung, Susy, Erlich, Henry A., Trachtenberg, Elizabeth A., Targan, Stephan R., McGovern, Dermot P.B., Heath, James R., Braun, Jonathan
Publicado em 2014

Linkage of CD-related serological phenotypes: NFKB1 haplotypes are associated with anti-CBir1 & ASCA, and show reduced NF-κB activation

Por Takedatsu, Hidetoshi, Taylor, Kent D, Mei, Ling, McGovern, Dermot P.B., Landers, Carol J, Gonsky, Rivkah, Cong, Yingzi, Vasiliauskas, Eric A, Ippoliti, Andrew, Elson, Charles O, Rotter, Jerome I, Targan, Stephan R
Publicado em 2008

MAGI2 genetic variation and inflammatory bowel disease (IBD)

Por McGovern, Dermot P.B., Taylor, Kent D., Landers, Carol, Derkowski, Carrie, Dutridge, Deb, Dubinsky, Marla, Ippoliti, Andy, Vasiliauskas, Eric, Mei, Ling, Mengesha, Emebet, King, Lily, Pressman, Sheila, Targan, Stephan R., Rotter, Jerome I.
Publicado em 2009

LRRK2 but not ATG16L1 is associated with Paneth cell defect in Japanese Crohn’s disease patients

Por Liu, Ta-Chiang, Naito, Takeo, Liu, Zhenqiu, VanDussen, Kelli L., Haritunians, Talin, Li, Dalin, Endo, Katsuya, Kawai, Yosuke, Nagasaki, Masao, Kinouchi, Yoshitaka, McGovern, Dermot P.B., Shimosegawa, Tooru, Kakuta, Yoichi, Stappenbeck, Thaddeus S.
Publicado no JCI Insight (2017)

Genetic Variants Synthesize to Produce Paneth Cell Phenotypes that Define Subtypes of Crohn’s Disease

Por VanDussen, Kelli L., Liu, Ta-Chiang, Li, Dalin, Towfic, Fadi, Modiano, Nir, Winter, Rachel, Haritunians, Talin, Taylor, Kent D., Dhall, Deepti, Targan, Stephan R., Xavier, Ramnik J., McGovern, Dermot P. B., Stappenbeck, Thaddeus S.
Publicado em 2013

Myeloid ATG16L1 facilitates host-bacteria interactions in maintaining intestinal homeostasis

Por Zhang, Hong, Zheng, Libo, McGovern, Dermot P. B., Hamill, Ariel M., Ichikawa, Ryan, Kanazawa, Yoshitake, Luu, Justin, Kumagai, Kotaro, Cilluffo, Marianne, Fukata, Masayuki, Targan, Stephan R., Underhill, David M., Zhang, Xiaolan, Shih, David Q.
Publicado no J Immunol (2017)

Genetic epistasis of IL23/IL17 pathway genes in Crohn’s disease

Por McGovern, Dermot P.B., Rotter, Jerome I., Mei, Ling, Haritunians, Talin, Landers, Carol, Derkowski, Carrie, Dutridge, Deb, Dubinsky, Marla, Ippoliti, Andy, Vasiliauskas, Eric, Mengesha, Emebet, King, Lily, Pressman, Sheila, Targan, Stephan R., Taylor, Kent D.
Publicado em 2009

A Disease-Associated Microbial and Metabolomics State in Relatives of Pediatric Inflammatory Bowel Disease Patients

Por Jacobs, Jonathan P., Goudarzi, Maryam, Singh, Namita, Tong, Maomeng, McHardy, Ian H., Ruegger, Paul, Asadourian, Miro, Moon, Bo-Hyun, Ayson, Allyson, Borneman, James, McGovern, Dermot P.B., Fornace, Albert J., Braun, Jonathan, Dubinsky, Marla
Publicado no Cell Mol Gastroenterol Hepatol (2016)