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Spatial and Temporal Stability of Paneth Cell Phenotypes in Crohn’s Disease: Implications for Prognostic Cellular Biomarker Development

BACKGROUND: We previously demonstrated that morphologic defects of ileal Paneth cells correlate with multiple susceptible genetic variants, the presence of granuloma, and clinical outcome in Crohn’s disease. These studies were performed using uninvolved areas of resection specimens. To develop Panet...

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Bibliographische Detailangaben
Hauptverfasser: Liu, Ta-Chiang, Gao, Feng, McGovern, Dermot P. B., Stappenbeck, Thaddeus S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180521/
https://ncbi.nlm.nih.gov/pubmed/24552829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.MIB.0000442838.21040.d7
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