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Spatial and Temporal Stability of Paneth Cell Phenotypes in Crohn’s Disease: Implications for Prognostic Cellular Biomarker Development

BACKGROUND: We previously demonstrated that morphologic defects of ileal Paneth cells correlate with multiple susceptible genetic variants, the presence of granuloma, and clinical outcome in Crohn’s disease. These studies were performed using uninvolved areas of resection specimens. To develop Panet...

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Autors principals: Liu, Ta-Chiang, Gao, Feng, McGovern, Dermot P. B., Stappenbeck, Thaddeus S.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180521/
https://ncbi.nlm.nih.gov/pubmed/24552829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.MIB.0000442838.21040.d7
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