Genetic Markers Predict Primary Nonresponse and Durable Response to Anti–Tumor Necrosis Factor Therapy in Ulcerative Colitis

BACKGROUND: Despite a high nonresponse rate, predictors of response to anti–tumor necrosis factor (anti-TNF) therapy in ulcerative colitis (UC) remain limited. We aim to determine clinical and genetic predictors of primary nonresponse (PNR) and durable response (DR) to anti-TNF therapy in a large pr...

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Detalhes bibliográficos
Publicado no:Inflamm Bowel Dis
Main Authors: Burke, Kristin E, Khalili, Hamed, Garber, John J, Haritunians, Talin, McGovern, Dermot P B, Xavier, Ramnik J, Ananthakrishnan, Ashwin N
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Original Clinical Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128143/
https://ncbi.nlm.nih.gov/pubmed/29718226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ibd/izy083
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