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Genetic markers predict primary non-response and durable response to anti-TNF biologic therapies in Crohn’s disease
BACKGROUND: One-fifth of patients with Crohn’s Disease (CD) are primary non-responders (PNR) to anti-tumor necrosis factor (anti-TNF) therapy, and an estimated 10–15% will fail therapy annually. Little is known about the genetics of response to anti-TNF therapy. The aim of our study was to identify...
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| Опубликовано в: : | Am J Gastroenterol |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5143156/ https://ncbi.nlm.nih.gov/pubmed/27596696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajg.2016.408 |
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