The TNF family member TL1A induces IL‐22 secretion in committed human T(h)17 cells via IL‐9 induction

TL1A contributes to the pathogenesis of several chronic inflammatory diseases, including those of the bowel by enhancing T(H)1, T(H)17, and T(H)2 responses. TL1A mediates a strong costimulation of these T(H) subsets, particularly of mucosal CCR9(+) T cells. However, the signaling pathways that TL1A...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Thomas, Lisa S., Targan, Stephan R., Tsuda, Masato, Yu, Qi T., Salumbides, Brenda C., Haritunians, Talin, Mengesha, Emebet, McGovern, Dermot P.B., Michelsen, Kathrin S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Inflammation, Extracellular Mediators, & Effector Molecules
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608031/
https://ncbi.nlm.nih.gov/pubmed/27733581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A0316-129R
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