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IL23R Haplotypes Provide A Large Population Attributable Risk for Crohn’s Disease

The IL-23 pathway plays a pivotal role in the development of chronic mucosal inflammation seen in the inflammatory bowel diseases. Multiple studies have now established the contribution of the interleukin 23 receptor gene (IL23R) to Crohn’s Disease (CD) risk in general and of the IL23R R381Q variant...

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Detalhes bibliográficos
Main Authors: Taylor, Kent D., Targan, Stephan R., Mei, Ling, Ippoliti, Andrew F., McGovern, Dermot, Mengesha, Emebet, King, Lily, Rotter, Jerome I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574614/
https://ncbi.nlm.nih.gov/pubmed/18470928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.20478
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