Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease

Genetic variation in both innate and adaptive immune systems is associated with Crohn's disease (CD) susceptibility, but much of the heritability to CD remains unknown. We performed a genome-wide association study (GWAS) in 896 CD cases and 3204 healthy controls all of Caucasian origin as defin...

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Detalhes bibliográficos
Main Authors: McGovern, Dermot P.B., Jones, Michelle R., Taylor, Kent D., Marciante, Kristin, Yan, Xiaofei, Dubinsky, Marla, Ippoliti, Andy, Vasiliauskas, Eric, Berel, Dror, Derkowski, Carrie, Dutridge, Deb, Fleshner, Phil, Shih, David Q., Melmed, Gil, Mengesha, Emebet, King, Lily, Pressman, Sheila, Haritunians, Talin, Guo, Xiuqing, Targan, Stephan R., Rotter, Jerome I.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Association Studies Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916706/
https://ncbi.nlm.nih.gov/pubmed/20570966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq248
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