Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease

Genetic variation in both innate and adaptive immune systems is associated with Crohn's disease (CD) susceptibility, but much of the heritability to CD remains unknown. We performed a genome-wide association study (GWAS) in 896 CD cases and 3204 healthy controls all of Caucasian origin as defin...

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Main Authors: McGovern, Dermot P.B., Jones, Michelle R., Taylor, Kent D., Marciante, Kristin, Yan, Xiaofei, Dubinsky, Marla, Ippoliti, Andy, Vasiliauskas, Eric, Berel, Dror, Derkowski, Carrie, Dutridge, Deb, Fleshner, Phil, Shih, David Q., Melmed, Gil, Mengesha, Emebet, King, Lily, Pressman, Sheila, Haritunians, Talin, Guo, Xiuqing, Targan, Stephan R., Rotter, Jerome I.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2010
主題:
Association Studies Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916706/
https://ncbi.nlm.nih.gov/pubmed/20570966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq248
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